Wound healing research has been hampered not only by multiple comorbidities in persons with chronic wounds, but also by poorly defined outcomes and variables, lack of standardization in data collection, and variations in the definition, measurement, and treatment of wounds. 28 This article visited specific classes of oral medications offered to improve wound healing, albeit with limited efficacy. We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services. 1. Int Adv Surg Oncol. 1981;4:15-58. The effect of chemotherapeutic agents on wound healing. Shamberger RC, Devereux DF, Brennan MF. A review of experimental studies of chemotherapeutic agents and wound healing has demonstrated impairment of healing by a wide variety of agents. Abstract. Introduction. Medications used to treat rheumatoid arthritis, such as corticosteroids, disease-modifying agents (DMARDs), and injectable biological agents (anti-TNFα), may have widespread effects on wound healing. Introduction. Medications used to treat rheumatoid arthritis, such as corticosteroids, disease-modifying agents (DMARDs), and injectable biological agents (anti-TNFα), may have widespread effects on wound healing. Comparing the influence of two immunosuppressants (fingolimod, azathioprine) on wound healing in a rat model of primary and secondary intention wound closure: Effect of fingolimod and azathioprine. Purpose. The cytotoxic and immunosuppressive effects of azathioprine, which mitigate the disease activity in inflammatory bowel disease, may compromise the healing of intestinal anastomoses leading to an increased risk of anastomotic leakage. Anyone have experience with post-surgical healing on azathioprine? I'm a bit more complicated than typical wound healing, I started with like a. Learn about the potential side effects of Imuran (azathioprine). Includes common and rare side effects information for consumers and healthcare professionals. As a single agent in a preclinical wound healing model in the rat, MMF in high dose has a negative effect on healing of the abdominal wall, which could possibly be prevented by delaying the medication for 3 days. No negative effect was found on the wound healing of bowel anastomoses.